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Rare Cancers

Lung Cancer






Rare Cancer Hospital in Banjara Hills, Hyderabad

Most cancer resources focus on common types. Rare cancers are often:

  • Misdiagnosed initially
  • Treated late due to unclear symptoms
  • Managed without molecular confirmation
  • Overlooked because they don’t “fit” common patterns

At Horizon Cancer Care, we evaluate rare cancers carefully, confirm pathology accurately, and initiate evidence-based treatment protocols.

About Rare Cancers

Rare cancers are those that occur infrequently in the general population. Because of their uncommon nature, they often require:

Sarcomas
Neuroendocrine tumors
Adrenal cancers
Thymic tumors
Rare head & neck cancers

Neuroendocrine Tumors  and GIST

Gastrointestinal Neuroendocrine Tumors
Pancreatic Neuroendocrine Tumors
Unknown Primary NET
Gastrointestinal Stromal Tumor (GIST)
Metastatic NET with liver involvement
Our Focus:
  • Detailed pathology review with Ki-67 grading
  • DOTATATE scan when indicated
  • Mutation testing (KIT / PDGFRA for GIST)
  • Targeted therapy (e.g., imatinib)
  • Long-term hormonal and systemic therapy planning
  •  PRRT- Peptide Receptor Radionuclide Therapy for advanced NET  through network centres

Rare GI and Hepatobiliary Tumors

Cholangiocarcinoma
Angiosarcoma liver
Hepatoblastoma in children
Appendix cancers
Psudomyxoma peritonei
Desmoid tumors
Our Focus:

Accurate diagnosis and treatment strategies

    •  molecular profiling when appropriate

Multidisciplinary management

  • surgical resection achieved by team of specialists
  • ⁠cytoreductive surgery and HIPEC ( Heated Intra Peritoneal Chemotherapy)

 

Rare Genitourinary Cancers

Adrenal cortical carcinoma
Rare kidney cancer variants
Squamous cancer of bladder
Prostate sarcoma/Ewings
Urethral cancers
Rare Testicular Tumor variants
Our Focus:
  • Organ-preserving approach when possible
  • Multimodality coordination (surgery + radiation + systemic therapy)
  • Hormonal and targeted therapy when indicated
  • Long-term surveillance

 Rare Head & Neck Tumors

Salivary gland tumors
Sarcomas soft tissue and bone
Nasopharyngeal carcinomas
Ear tumors
Nerve sheath tumors
Lymphomas and variety of benign
Lymphomas and variety of benign tumors
Our Focus:
  • Accurate histological subtyping
  • Radiation coordination
  • Systemic therapy integration
  • Structured follow-up

Rare Hematologic Malignancies

Multiple Myeloma
Myelodysplastic Syndrome (MDS)
Myeloproliferative Neoplasms (MPN)
Rare leukemias (e.g., Hairy Cell Leukemia)
Our Focus:
  • Decisions based on multidisciplinary team
  • Advanced treatments in collaboration with specialist centres

Pediatric Cancers (Childhood Cancers)

Cancer in children is rare compared to adults, but it requires specialized evaluation and treatment.
Unlike adult cancers, pediatric cancers are usually:

Not related to lifestyle factors
Often linked to developmental or genetic changes
Rapid-growing but frequently highly treatment-responsive
Common childhood cancers include:
Leukemia
Brain tumors
Lymphomas
Wilms tumor
Neuroblastoma

Pediatric oncology requires dedicated protocols, age-specific chemotherapy dosing, and multidisciplinary pediatric support. When indicated, our patients treated in collaboration with pediatric oncology centers for comprehensive management.

When Should You Seek Re-Evaluation for a rare cancer?

Symptoms persist despite treatment
Diagnosis feels unclear
Report mentions “rare variant”
Cancer is not responding as expected
Treatment options were presented as limited

Our Clinical Philosophy for Rare Cancers

Confirm diagnosis before committing to therapy
Review pathology when needed
Use molecular testing appropriately
Avoid overtreatment when disease is indolent
Escalate treatment promptly when aggressive

FAQ’s

  • Not necessarily. Some rare cancers grow very slowly and can be managed for many years, while others may behave aggressively. The outcome depends more on the tumor biology and stage at diagnosis than on how common it is.

Reviewed By

Medically Reviewed by : Dr. Srinivas Prasad, MCh (Surgical Oncology)
20+ years of experience in oncologic surgery and multidisciplinary cancer care.
Registration No: 2111
Last reviewed: February 2026

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