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Esophageal and Upper GI cancers

Treatment Care

Surgical Oncology
Chemotherapy
Immunotherapy and Targeted Therapy
Radiation Therapy
Diagnosis
Multispeciality Support
Structured Patient Support

    Best Gastrointestinal Cancer Hospital in Banjara Hills, Hyderabad

    Esophageal, Gastric and Small Intestinal Cancers

    Upper GI cancers affect the food pipe, stomach, and small intestine.These cancers often begin silently with mild acidity, difficulty swallowing, vague abdominal discomfort. At Horizon Cancer Centre (HCC), we approach upper GI cancers with precision diagnostics, molecular profiling, organ-preserving surgery, and advanced systemic therapies tailored to tumor biology.

    Esophageal Cancer

    Affects the food pipe, often identified by progressive difficulty swallowing, weight loss, and persistent reflux.

    Types

    Squamous cell
    Adenocarcinoma

    Genetic Evaluation

    HER2, PD-L1, MSI

    Treatment Approach

    EMR, minimally invasive esophagectomy, neoadjuvant chemoradiation, immunotherapy (Nivolumab/Pembrolizumab).

    Gastric Cancer

    Common symptoms include early satiety, bloating, anemia, and unexplained weight loss.

    Multidisciplinary Strategy

    Staging laparoscopy, D2 lymph node dissection, FLOT protocols.

    Hereditary Considerations

    CDH1 mutation screening and counseling.

    Targeted Therapy

    Trastuzumab, Ramucirumab, Nivolumab/Pembrolizumab.

    Small Intestinal Cancer

    Less common but complex tumors requiring specialized surgical and systemic management.

    Types

    Adenocarcinoma
    Neuroendocrine
    GIST

    Genetic Links

    Lynch syndrome, FAP, Peutz-Jeghers.

    Treatment Approach

    Segmental resection, targeted therapy tailored to specific tumor markers.

    Our Treatment Philosophy

    Focus on the specific genetic and molecular blueprint of your cancer to ensure the highest chance of success.

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    FAQ’s

    • Upper GI cancers include cancers of the esophagus (food pipe), stomach, and small intestine. These cancers affect the upper digestive tract and may cause symptoms related to swallowing, digestion, or unexplained weight loss.

    When Should You Seek Evaluation?

    Persistent difficulty or pain when swallowing
    Unexplained and significant weight loss
    Early satiety (feeling full after just a few bites)
    Persistent bloating or gastrointestinal discomfort
    New or worsening anemia (chronic fatigue)

    Why Choose Horizon Cancer Centre?

    Advanced molecular diagnostics
    Access to immunotherapy & targeted drugs
    Minimally invasive GI oncology surgery
    Genetic counselling for hereditary cancers
    Long-term follow-up care model

    Reviewed By

    Medically Reviewed by : Dr. Srinivas Prasad, MCh (Surgical Oncology)
    20+ years of experience in oncologic surgery and multidisciplinary cancer care.
    Registration No: 2111
    Last reviewed: February 2026